Penis&Scrotom برای بزرگنمایی عکسها کلیک را روی ان نگه دارید..... Figure 28.1 Median Raphe Cyst. This probably results from cystic dilation of accessory urethral canals or periurethral ducts Figure 28.2 Mucoid Cyst of Penis. The lesion is lined by stratified columnar epithelium containing mucin-secreting cells Figure 28.3 Lichen Sclerosus. A, The dense hyalinized band of dermal collagen, chronic lymphocytic inflammation, and loss of rete ridges is characteristic. B, Acanthosis and hyperkeratosis defines squamous hyperplasia, in this case associated with lichen sclerosus Figure 28.4 Syphilis. A, The dense plasma cell-rich inflammatory infiltrate, often around blood vessels, is characteristic. B, Immunostain for Trepo- nema pallidum Figure 28.5 Herpes with prototypical viral cytopathic effect at the edge of the ulcer Figure 28.6 Peyronie Disease. The lesion is composed of densely hyalinized tissue that has undergone focal dystrophic calcification Figure 28.7 Large Lesions of Condyloma Acuminatum in an HIV- Infected Patient. The glans penis also shows herpesvirus infection Figure 28.8 Condyloma Acuminatum. A, Complex papillary pattern composed of well-differentiated squamous epithelium is seen. B, Virus- induced cytopathic changes are present Figure 28.9 Some condylomas have a low-power appearance simulating seborrheic keratosis Figure 28.10 Outer aspect of squamous cell carcinoma of the glans penis showing a papillomatous pattern of growth Figure 28.11 Penile squamous cell carcinoma with extensive involvement of the prepuce (foreskin) Figure 28.12 Basaloid penile intraepithelial neoplasia (PeIN) Figure 28.13 Warty-basaloid penile intraepithelial neoplasia (PeIN) Figure 28.14 Differentiated penile intraepithelial neoplasia (PeIN) Figure 28.15 Invasive basaloid carcinoma of penis, an HPV-related variant of squamous cell carcinoma Figure 28.16 Invasive warty carcinoma is characterized by well-developed koilocytotic atypia Figure 28.17 A, Invasive squamous cell carcinoma, usual type, shows irregular invasion of underlying stroma without features of other subtypes. B, Moderately differentiated invasive squamous cell carcinoma, usual type Figure 28.18 Verrucous carcinoma is characterized by a broad-based "pushing" interface with underlying stroma Figure 28.19 Carcinoma cuniculatum often has a central opening simulat- ing a cyst Figure 28.20 Pseudohyperplastic Squamous Cell Carcinoma. A, On low power, there are markedly irregular invaginations of squamous epithelium. B, The histologic features are extremely well differentiated Figure 28.21 Squamous Cell Carcinoma of Penis With Spindle Cell (Sarcomatoid) Features. There is a blending of the carcinoma islands with the sarcoma-like component Figure 28.22 Extramammary Paget Disease. A, A population of atypical cells with clear cytoplasm, either as singe cells or clusters, involves the epidermis. B, Cytokeratin 7 shows strong cytoplasmic reactivity Figure 28.23 Urothelial carcinoma of penile urethra Figure 28.24 Malignant melanoma presenting as a polypoid blue colored mass protruding from the urethra Figure 28.25 Myointimoma of the corpus spongiosum Figure 28.26 Idiopathic Calcinosis of Scrotum. (Courtesy of Dr. JuanJ (Segura, San José, Costa Rica. Figure 28.27 Idiopathic calcinosis of scrotum, with accompanying foreign body-type giant cell reaction Figure 28.28 Sclerosing Lipogranuloma of Scrotum. Prominent histiocytic and multinucleated giant cell reaction around empty spaces, which presumably contained lipid material Figure 28.29 Massive Localized Lymphedema of the Scrotum. The lobular collections of capillary sized blood vessels are typical Figure 28.30 Gross appearance of vascular leiomyoma of scrotum Figure 28.31 Leiomyoma of tunica dartos