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Ackerman Atlas(chaptr28)

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Penis&Scrotom

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 Figure 28.1 Median Raphe Cyst. This probably results from cystic dilation of accessory urethral canals or periurethral ducts

Figure 28.2 Mucoid Cyst of Penis. The lesion is lined by stratified columnar epithelium containing mucin-secreting cells

Figure 28.3 Lichen Sclerosus. A, The dense hyalinized band of dermal collagen, chronic lymphocytic inflammation, and loss of rete ridges is characteristic. B, Acanthosis and hyperkeratosis defines squamous hyperplasia, in this case associated with lichen sclerosus

 Figure 28.4 Syphilis. A, The dense plasma cell-rich inflammatory infiltrate, often around blood vessels, is characteristic. B, Immunostain for Trepo- nema pallidum

Figure 28.5 Herpes with prototypical viral cytopathic effect at the edge of the ulcer

 Figure 28.6 Peyronie Disease. The lesion is composed of densely hyalinized tissue that has undergone focal dystrophic calcification

Figure 28.7 Large Lesions of Condyloma Acuminatum in an HIV- Infected Patient. The glans penis also shows herpesvirus infection

 Figure 28.8 Condyloma Acuminatum. A, Complex papillary pattern composed of well-differentiated squamous epithelium is seen. B, Virus- induced cytopathic changes are present

Figure 28.9 Some condylomas have a low-power appearance simulating seborrheic keratosis

 Figure 28.10 Outer aspect of squamous cell carcinoma of the glans penis showing a papillomatous pattern of growth

Figure 28.11 Penile squamous cell carcinoma with extensive involvement of the prepuce (foreskin)

 Figure 28.12 Basaloid penile intraepithelial neoplasia (PeIN)

Figure 28.13 Warty-basaloid penile intraepithelial neoplasia (PeIN)

Figure 28.14 Differentiated penile intraepithelial neoplasia (PeIN)

 Figure 28.15 Invasive basaloid carcinoma of penis, an HPV-related variant of squamous cell carcinoma

Figure 28.16 Invasive warty carcinoma is characterized by well-developed koilocytotic atypia

 

 Figure 28.17 A, Invasive squamous cell carcinoma, usual type, shows irregular invasion of underlying stroma without features of other subtypes. B, Moderately differentiated invasive squamous cell carcinoma, usual type

 

Figure 28.18 Verrucous carcinoma is characterized by a broad-based "pushing" interface with underlying stroma

 

 Figure 28.19 Carcinoma cuniculatum often has a central opening simulat- ing a cyst

 

Figure 28.20 Pseudohyperplastic Squamous Cell Carcinoma. A, On low power, there are markedly irregular invaginations of squamous epithelium. B, The histologic features are extremely well differentiated

 

 Figure 28.21 Squamous Cell Carcinoma of Penis With Spindle Cell (Sarcomatoid) Features. There is a blending of the carcinoma islands with the sarcoma-like component

 

 Figure 28.22 Extramammary Paget Disease. A, A population of atypical cells with clear cytoplasm, either as singe cells or clusters, involves the epidermis. B, Cytokeratin 7 shows strong cytoplasmic reactivity

 

Figure 28.23 Urothelial carcinoma of penile urethra

Figure 28.24 Malignant melanoma presenting as a polypoid blue

colored mass protruding from the urethra

 

 Figure 28.25 Myointimoma of the corpus spongiosum

Figure 28.26 Idiopathic Calcinosis of Scrotum. (Courtesy of Dr. JuanJ

(Segura, San José, Costa Rica.

 

 Figure 28.27 Idiopathic calcinosis of scrotum, with accompanying foreign body-type giant cell reaction

 

Figure 28.28 Sclerosing Lipogranuloma of Scrotum. Prominent histiocytic and multinucleated giant cell reaction around empty spaces, which presumably contained lipid material

 

Figure 28.29 Massive Localized Lymphedema of the Scrotum. The lobular collections of capillary sized blood vessels are typical

 

Figure 28.30 Gross appearance of vascular leiomyoma of scrotum

 

 Figure 28.31 Leiomyoma of tunica dartos