Parathyroid برای بزرگنمایی عکسها کلیک را روی ان نگه دارید Figure 9.1 A and B, Gross appearance of two parathyroid adenomas. Note the roundish shape, the homogeneous appearance interrupted by a few foci of fresh hemorrhagic or cystic changes, and the brown to yellowish color Figure 9.2 Parathyroid adenoma arising from the left lower parathyroid gland Figure 9.3 Parathyroid adenoma. The tumor is hypercellular, homoge- neous, and well vascularized Figure 9.4 Parathyroid adenoma with clusters of bizarre nuclei. This feature is not an indication of malignancy Figure 9.5 Parathyroid adenoma with follicular structures containing a colloid-like material simulating thyroid Figure 9.6 Heavy lymphocytic infiltrate within a parathyroid adenoma Figure 9.7 Parathyroid adenoma composed of an admixture of chief cells and oncocytic cells Figure 9.8 Chief cell hyperplasia with multinodular pattern of growth Figure 9.9 A and B, Parathyroid gland with chief cell hyperplasia that has been surgically transplanted into the forearm. The clusters of hyperplastic chief cells infiltrate the skeletal muscle, thus simulating carcinoma Figure 9.10 Water-clear cell hyperplasia. Note the chocolate brown color, the pseudopods, and the greater involvement of the upper glands. (Redrawn from Castleman B. Tumors of the Parathyroid Glands. Atlas of Tumor Pathology, series 1, fascicle 15. Washington, DC: Armed Forces Institute of Pathology; 1952.) Figure 9.11 Water-clear cell hyperplasia. The cells are very large, optically clear, and have sharply outlined cell membranes Figure 9.12 Parathyroid carcinoma. A, Sharply outlined fibrous bands incompletely dividing the tumor into lobules. B, Mitotic features Figure 9.13 Parathyroid carcinoma with lymphovascular invasion Figure 9.14 High-grade parathyroid carcinoma with abundant mitotic figures Figure 9.15 Historical example of extreme osteitis fibrosa cystica. Note deformity of bone with numerous cysts and brown tumors. (From Hunter D, Turnbull HN. Hyperparathyroidism. Generalized osteitis fibrosa, with observations upon bones, parathyroid tumors, and normal parathyroid glands. Br J Surg. 1931;19:203-284.) Figure 9.16 A, Extensive changes in bones of pelvis and femur caused by functioning parathyroid adenoma. B, Same pelvis and femur 8 years after removal of adenoma. Note complete reversion to normal. (From Black BK, Ackerman LV. Tumors of the parathyroid. A review of twenty-three cases. Cancer. 1950;3:415-444.) Figure 9.17 A, Cystic changes and cortical alterations in bones of hands of patient with functioning parathyroid adenoma. B, Dramatic reparative change evident 9 months after removal of adenoma Figure 9.18 Bone changes in hyperparathyroidism. There is marked resorption of bone trabeculae and clustering of osteoclasts
